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Superstable lipid vacuoles endow cartilage with its shape and biomechanics | Science Conventionally, the size, shape, and biomechanics of cartilages are determined by their voluminous extracellular matrix. By contrast, we found that multiple murine cartilages consist of lipid-filled cells called lipochondrocytes. Despite resembling ...
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Sexually dimorphic dopaminergic circuits determine sex preference | Science Sociosexual preference is critical for reproduction and survival. However, neural mechanisms encoding social decisions on sex preference remain unclear. In this study, we show that both male and female mice exhibit female preference but shift to male ...
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Decoding the molecular interplay of CD20 and therapeutic antibodies with fast volumetric nanoscopy | Science Elucidating the interaction between membrane proteins and antibodies requires whole-cell imaging at high spatiotemporal resolution. Lattice light-sheet (LLS) microscopy offers fast volumetric imaging but suffers from limited spatial resolution. DNA-based ...
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Local genetic adaptation to habitat in wild chimpanzees | Science How populations adapt to their environment is a fundamental question in biology. Yet, we know surprisingly little about this process, especially for endangered species, such as nonhuman great apes. Chimpanzees, our closest living relatives, are ...
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News at a glance: Snail darter’s true identity, diverse proteins, and high-profile bacteria The latest in science and policy
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Starved of sediment, an iconic piece of the Mississippi River delta could vanish The Bird's Foot, critical for shipping and wildlife, is “one of the most threatened places in America”
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Grazing can reduce wildfire risk amid climate change | Science Over half of Earth’s land surface is covered with fire-prone vegetation, with grassy ecosystems—such as grasslands, savannas, woodlands, and shrublands—being the most extensive. In the context of the climate crisis, scientists worldwide are exploring ...
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Building materials could store more than 16 billion tonnes of CO2 annually | Science Achieving net-zero greenhouse gas emissions likely entails not only lowering emissions but also deploying carbon dioxide (CO2) removal technologies. We explored the annual potential to store CO2 in building materials. We found that fully replacing ...
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Tropical forest clearance impacts biodiversity and function, whereas logging changes structure | Science The impacts of degradation and deforestation on tropical forests are poorly understood, particularly at landscape scales. We present an extensive ecosystem analysis of the impacts of logging and conversion of tropical forest to oil palm from a large-...
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Dietary breadth in kangaroos facilitated resilience to Quaternary climatic variations | Science Identifying what drove the late Pleistocene megafaunal extinctions on the continents remains one of the most contested topics in historical science. This is especially so in Australia, which lost 90% of its large species by 40,000 years ago, more than ...
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Photonic axion insulator | Science Axions, hypothetical elementary particles that remain undetectable in nature, can arise as quasiparticles in three-dimensional crystals known as axion insulators. Previous implementations of axion insulators have largely been limited to two-dimensional ...
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Parallel gene expansions drive rapid dietary adaptation in herbivorous woodrats | Science How mammalian herbivores evolve to feed on chemically defended plants remains poorly understood. In this study, we investigated the adaptation of two species of woodrats (Neotoma lepida and N. bryanti) to creosote bush (Larrea tridentata), a toxic shrub ...
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In Other Journals | Science Editors’ selections from the current scientific literature
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In Science Journals | Science Highlights from the Science family of journals
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Teaming up to save Argentine Chaco forests | Science HomeScienceVol. 387, No. 6730Teaming up to save Argentine Chaco forestsBack To Vol. 387, No. 6730 Full accessLetterOutside the Tower Share on Teaming up to save Argentine Chaco forestsMatias Mastrangelo and Micaela CaminoAuthors Info & AffiliationsScience9 Jan 2025Vol 387, Issue 6730p. 148DOI: 10.1126/science.ads8911 PREVIOUS ARTICLEGreen building materials undercut EU plastic goalsPreviousNEXT A…
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Green building materials undercut EU plastic goals | Science HomeScienceVol. 387, No. 6730Green building materials undercut EU plastic goalsBack To Vol. 387, No. 6730 Full accessLetter Share on Green building materials undercut EU plastic goalsAnna Cipriani [email protected], Federico Lugli, and Vittorio MaselliAuthors Info & AffiliationsScience9 Jan 2025Vol 387, Issue 6730pp. 147-148DOI: 10.1126/science.adt2152 PREVIOUS ARTICLEFailure to replicatePrevious…
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Failure to replicate | Science A historian confronts the complicated origins and uncertain future of priming research
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The many misuses of the rape kit | Science Haphazardly applied, frequently lost, and often ignored, the vital forensic tool also has a troubling past
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Impacts of EPA’s finalized power plant greenhouse gas standards | Science Emissions reductions may be met with relatively small costs
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Stress drives a switch in sex preference | Science Distinct brain circuits control sex preferences in mice
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Ena-bile-ing liver cancer growth | Science Bile acids differentially affect immune cell responses to liver cancer
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A long-ignored skeletal tissue filled with oil | Science Lipid-rich cartilage points to nonmetabolic functions of lipid vacuoles in mammals
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Built to remove carbon | Science Building materials could facilitate long-term removal of atmospheric carbon dioxide
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A river with a mind of its own | Science HomeScienceVol. 387, No. 6730A river with a mind of its ownBack To Vol. 387, No. 6730 Full accessFeature Share on A river with a mind of its ownWarren CornwallAuthors Info & AffiliationsScience9 Jan 2025Vol 387, Issue 6730p. 130DOI: 10.1126/science.adv7636 PREVIOUS ARTICLELosing groundPreviousNEXT ARTICLEGrazing can reduce wildfire risk amid climate changeNext NotificationsBookmark ContentsInfor…
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Optimism for a global plastics treaty | Science The lack of consensus at the United Nations (UN) global plastics treaty negotiations in December may seem like a setback, but declaring the talks a failure is premature. The process has not collapsed but has been extended, with further negotiations ...
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Scientists uncover how the brain washes itself during sleep Pulsating blood vessels push fluid into and out of the brains of slumbering mice
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‘Good boy!’ Truffle-sniffing dogs are helping uncover hidden underground ecosystems Their keen noses are helping researchers document the diversity of fungi living underneath Pacific Northwest forests
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As academic Bluesky grows, researchers find strengths—and shortcomings Platform fosters collegial interactions among scientists, but potentially limits interactions beyond the academic community
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Fish implanted with tumor cells could help oncologists quickly personalize cancer treatments The first clinical trial of zebrafish embryos acting as cancer “avatars” will start soon
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NIH launches initiative to double check biomedical studies But so far, few investigators seem interested in having a contract lab repeat their experiments
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